Using Herbal Therapy to treat Hepatitis C and Cirrhosis

1. Summary of Hepatitis C

The hepatitis C virus (HCV) is one main causes of chronic liver disease in Western countries. It accounts for about 13 to 18 percent of acute viral hepatitis, 60 to 70 percent of chronic hepatitis, and up to 55 percent of cirrhosis, end-stage liver disease, and liver cancer.

A distinct and major characteristic of hepatitis C is its tendency to cause chronic liver disease. At least 70 percent of patients with acute hepatitis C ultimately develop chronic infection, and most of these patients have accompanying chronic liver diseases.

Chronic hepatitis C can cause cirrhosis, liver failure, and liver cancer. Researchers estimate that at least 20 percent of patients with chronic hepatitis C develop cirrhosis, a process that takes at least 10 to 20 years. After 20 to 40 years, a smaller percentage of patients with chronic disease develop liver cancer.

2. Getting Tested:

A.HCV RNA
HCV RNA tests directly measure for the presence of the hepatitis C virus. HCV RNA tests may be qualitative or quantitative. Qualitative HCV RNA tests are used to diagnose hepatitis C. The doctor might choose to perform an HCV RNA test instead of the ELISA, especially if patients are at high-risk for hepatitis C. The HCV RNA test will be positive in as little as 1 to 2 weeks after exposure. A positive HCV RNA test means a person has hepatitis C infection.

Quantitative HCV RNA tests allow doctor to determine exactly how much virus is in the blood. This is referred to as the viral load. The viral load is usually expressed as units per milliliter or copies per milliliter. In patients with chronic hepatitis C infection, viral loads vary widely from 50,000 to 5 million copies per milliliter. A higher viral load may not necessarily be a sign of more severe or more advanced disease but it does correlate with likelihood to respond to treatment. HCV RNA tests can also be used to monitor response to hepatitis C treatment. For example, if the viral load decreases during treatment, this suggests that treatment is working and should be continued. Conversely, if the viral load remains the same, it suggests that the patient is not responding to treatment.

B. ALT
The ALT test is a blood test that measures levels of alanine aminotransferase (ALT), a liver enzyme that is produced in higher amounts when the liver is inflamed. High ALT levels can be a sign of hepatitis C, but other conditions can also cause an increase in ALTs, including heart attacks, high triglyceride levels, and other forms of hepatitis.

On the other hand, many people with hepatitis C have fluctuating or normal ALT levels, so a normal ALT test does not necessarily mean that hepatitis C infection can be ruled out.

ALTs are measured in routine blood tests so if annual blood work results indicate high ALT levels, this may alert doctor to do further tests to find out the cause.

A higher than normal ALT level does not necessarily mean more serious disease.

C. ELISA
The most commonly used initial blood test for hepatitis C is the enzyme-linked immunosorbent assay (ELISA). The ELISA is also sometimes referred to as the EIA. The ELISA tests for the presence of antibodies to the hepatitis C virus. An antibody is a type of immune protein molecule that is produced when bacteria or viruses enter the body. A specific antibody is manufactured against each invader.

In most cases if ELISA test is negative, it means that patients do not have antibodies to the hepatitis C virus and do not need to be tested further. Although false-negative tests are very rare with the ELISA, they may sometimes occur in patients whose immune systems do not produce enough antibodies, such as people on hemodialysis and people with immune disorders (eg, HIV positive persons).

If patients have a high-risk for acquiring hepatitis C and ELISA test is negative, doctor may want to screen again after a few months. Sometimes antibody tests such as the ELISA might not become positive for 3 to 6 months after a person is infected.

If the ELISA is positive, this generally means that there are antibodies against HCV in blood; however, it does not necessarily mean that you have hepatitis C. It may be that you were infected in the past and have already cleared the infection. If the ELISA test is positive, doctor or the specialist will probably perform an HCV RNA test to determine whether there is still virus in blood or whether patients have cleared the infection. In very rare cases, the ELISA may give a false-positive result, such as in people with autoimmune disorders. Again, these can be results can be confirmed with an HCV RNA test.

D. RIBA
The recombinant immunoblot assay (RIBA) is another test that detects the presence of antibodies to hepatitis C virus in the blood. The RIBA can be used to confirm a positive ELISA , for example, in a blood donor who does not appear to have risk factors for hepatitis C. Blood banks also use the RIBA to test donated blood, especially to confirm blood samples that are HCV-positive by the ELISA.

3. Western Treatment
Combination therapy of Alpha interferon and Ribavirin leads to rapid improvements in serum ALT levels and disappearance of detectable HCV RNA in up to 60 percent of patients. However, long-term improvement in hepatitis C occurs only if HCV RNA disappears during therapy and stays undetectable once therapy is stopped. Among patients who become HCV RNA negative during treatment, a large proportion relapse when therapy is stopped.
Patients with genotypes 2 and 3 have a high rate of response to combination treatment. In contrast, patients with genotype 1 have a lower rate of response to combination therapy. Interferon monotherapy is also recommended for some patients.

4. Side Effects of Western Medicine
Common side effects of alpha interferon and peginterferon (occurring in more than 10 percent of patients) include

1.
  • fatigue
2. muscle aches
3. headaches
4. nausea and vomiting
5. skin irritation at the injection site
6. low-grade feverweight loss
7. irritability
8. depression
9. mild bone marrow suppression
10. hair loss (reversible)
   
  • Ribavirin also causes side effects, and the combination is generally less well tolerated than interferon monotherapy. The most common side effects of ribavirin are

  •   anemia
      fatigue and irritability
      itching
      skin rash
      nasal stuffiness, sinusitis, and cough
      fatigue
      shortness of breath,
      palpitations, and
      headache.


5. Hepatitis Recovery Capsule

After more than 6 years of clinical experiment, Hepatitis Recovery Capsule has been verified to be very effective in conquering the disease and the proportion of more-than-1-year disappearance of HCV RNA after receiving the therapy can reach 69.00%. In the same time, there are no eminent side effects when taking the medicine. Why it is so difficult to find effective medicine to treat the disease? You may ask. The reason is HCV stays in nucleolus of liver cells and common circumstances may often be like this: if the HCV be killed the normal liver cells will incur large damage in the same time.

Yet, the formula formation of Hepatitis Recovery Capsule gives significant consideration to this issue and new wild herbs are used to bring the effective components into the nucleolus of liver cells to directly excert effects upon the virus while not hurting normal cells.

The one component of Hepatitis Recovery Capsule is the rare herbs collected in Autumn season from Changbai mountain. The altitude of Changbai mountain is 1,350 meters high. Putting the plant indoors and giving observation, you can note the plant can emit minor light after turning off the light. By scientific analysis, researchers know the herb has a large amount of rare microelement that human beings need the most which most of wild plants cannot assimilate so much. Also in the formula, we add Hongjingtian (resist high temperature, tolerate tiredness), American ginseng (nourish Yin and benefit Chi), indigo wood root (neutralize poison, cool the blood and benefit liver), and other traditional Chinese herbs.

The characteristics are:

1. The flavor is mild, neither cold nor dry, and suit for the physiology characteristic of liver. At the same time it also has the original effect of strengthening the liver and spleen, to stimulate liver and to neutralize poison.The pharmacody is to improve the blood circulation of the liver, and increase the blood flow in liver area and oxygen content of the cell, to accelerate rebirth of hepatic cell, to enhance the virus resistant capability of the liver, and kill the virus gradually. And it also has the effect to improve liver fibrosis, to correct inversion of protein, to turn swelling liver to normal, and eliminate ascites due to hepatocirrhosis.

2.In the Hepatitis Recovery Capsule there are components be capable of soakage and infiltration, so it can make the effective component of the drug to infiltrate into the nucleus of hepatic cell, and exert their treating effect better, thus eliminating Hepatitis C Virus.

3 .Treating the root and tip simultaneously. After the HCV RNA turning negative, almost no recurrence happened if patients can take the medicine foe sometime more.

4. All the herbs used in the formula are from natural plant living environment, the long-time orally taking has been verified to be free of any prominent side effects.

After taking for 3-5 days, the following symptoms begin to disappear, such as: breast suffocation, hepatic region pain, dry mouth, feeling bitter with mouth, abdominal distention, inappetence, nausea, fatigue, dizziness, insomnia, feeling sour and feeble with waist and knees, yellow urination, loose bowels, and so on.

Generally speaking, 3 months later some patients can show their HCV RNA decrease considerably or turns to negative. Patients are advised to continue to take the medicine for some time, in order to increase albumin (A) in vivo, and decrease globulin (G) in the same time.

6. Clinical Experiment Results
(In comparison with combination therapy of alpha interferon and ribavirin)

(1)After 2 months
A Group: Combination therapy of alpha interferon and ribavirin
B Group: Taking Hepatitis Recovery Capsule

 

HCV RNA Disappearance Proportion

Viral load with HCV RNA Present Patients

Liver Biopsy Scores

A Group
31.0%
32 ± 10
11 ± 5
B Group
70.5%
18 ± 13
30 ± 3

(2)After 4 months
A Group: Combination therapy of alpha interferon and ribavirin
B Group: Taking Hepatitis Recovery Capsule

 

HCV RNA Disappearance Proportion

Viral load with HCV RNA Present Patients

Liver Biopsy Scores

A Group
53.4%
13 ± 8
27 ± 3
B Group
72.5%
9 ± 6
60 ± 3

 

7. Conclusion
Given the fact that the proportion of more-than-1-year disappearance of HCV RNA after receiving the therapy can reach 69.00% and there is no prominent side effects for long term taking, Hepatitis Recovery Capsule is much more effective than combination therapy of alpha interferon and ribavirin.


Theelin Hepatitis Prevention and Treatment Hospital
109 Meigui Street
Shuangta District, Chaoyang, China 122000
Tel: 0086-133-8689-0186
Fax: 0086-139-988-62461


 


 

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